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Diaphramatic dysfunction caused by ventilators in Recipients and Donors scheduled for Living Donor Liver Transplantatio

Not Applicable
Conditions
Health Condition 1: J986- Disorders of diaphragm
Registration Number
CTRI/2024/07/071019
Lead Sponsor
Institute Of Liver And Biliary Sciences Vasnt KunjNew Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients with chronic liver disease

Exclusion Criteria

Pediatric patients

Patients with neuromuscular disorders

Previous major thoracic or abdominal surgery (both donors and

recipients)

Acute liver failure

Repeat transplantation and surgerY

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To study the incidence of ventilator induced diaphragmatic <br/ ><br>dysfunction in recipients and donors scheduled for living donor liver <br/ ><br>transplantationTimepoint: 24 hours
Secondary Outcome Measures
NameTimeMethod
To evaluate the diaphragm function (Excursion and Thickening Fraction) <br/ ><br>using Ultrasound in cirrhotic patients undergoing LDLT and compare it with <br/ ><br>Healthy Donors. <br/ ><br>• To study the prevalence of pre-existing Diaphragmatic Dysfunction in <br/ ><br>recepients of living donor liver transplantation. <br/ ><br>• The association of Ascites, Pleura Effusion, and Sarcopenia with <br/ ><br>Diaphragmatic Dysfunction – Predictors of Diaphramatic dysfunctionTimepoint: 24 hours
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