Effect of splenectomy combined with traditional Chinese medicine on liver function in patients with hepatolenticular degeneration and hypersplenism

Not Applicable

• Conditions: Wilson's disease

• Registration Number: ITMCTR2000003431
• Lead Sponsor: The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients with HLD and hypersplenism who meet the above diagnosis criteria of hepatolenticular degeneration and TCM syndrome, and patients who meet the imaging diagnosis and surgical indications;
2. Children Pugh grade A and B patients;
3. The patients with moderate or severe hypersplenism were diagnosed by color ultrasound, blood examination and bone marrow puncture;
4. Written informed consent signed by the subject or his family (Guardian) to participate in the test.

Exclusion Criteria

1. The patient who lost the interview or left the patient who was not rigorous;
2. Patients with severe cardiopulmonary and other serious diseases;
3. In the last three months, patients who use hormone or other drugs, including traditional Chinese medicine prescriptions and proprietary Chinese medicine, may affect the results.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transaminases (glutamic-pyruvic transaminase and glutamic-oxaloacetic transaminase);Protein (albumin, prealbumin);Bilirubin (total bilirubin, direct bilirubin);