on-alcoholic fatty liver disease in obese children: long-term effects of a lifestyle intervention. Follow-up study of a cohort

• Conditions: non-alcoholic fatty liver disease; fatty liver; 10019654; 10013317

• Registration Number: NL-OMON32646
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

- Presence of NAFLD determined by 1H-MRS before treatment
- Completion of at least 2 months of life style intervention at Heideheuvel institute
- Liver fat determined by 1H-MRS after treatment

Exclusion Criteria

Other liver disease
Significant alcohol consumption
Use of steatogenic drugs

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Change in percentage of liver steatosis between end of treatment in previous<br /><br>study and one year later. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation between change in liver steatosis and changes in a panel of risk<br /><br>factors.<br /><br>Change in status of carotid atherosclerosis between start of treatment in<br /><br>previous study and one year later and correlation with change in the perentage<br /><br>of liver steatosis.</p><br>