跳至主要内容
临床试验/CTRI/2024/06/069424
CTRI/2024/06/069424尚未招募不适用

Spectrum of infections and efficacy of procalcitonin in detecting sepsis in decompensated cirrhotic patients.

NA1 个研究点 分布在 1 个国家目标入组 135 人开始时间: 2025年5月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
135
试验地点
1
主要终点
To study the spectrum of various infections in patients with

研究概览

简要总结

Patients who are diagnosed with decompensated cirrhosis after obtaining written informed consent and checking for exclusion criteria will be enrolled in the study. Information regarding relevant history, physical examination and laboratory parameters will be entered in a preformatted data sheet. Baseline severity scores such as the CTP, MELD Na and qSOFA will be calculated. Patients with suspected infections will be screened based on the clinical condition, laboratory parameters, radiological findings and culture reports. As per the protocol serum procalcitonin has been routinely used as a marker in all patients suspected of infections in our department. In these patients procalcitonin will be determined within the first 12 hours of admission.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • Age more than 18 years Patients diagnosed with cirrhosis.
  • Patient with evidence of Systemic inflammatory response syndrome and presence of infection.

排除标准

  • Patients diagnosed as Acute-on-chronic liver failure as per APASL definition.
  • Patients who are diagnosed with HCC.

结局指标

主要结局

To study the spectrum of various infections in patients with

时间窗: 6 months

decompensated cirrhosis.

时间窗: 6 months

次要结局

  • To assess the efficacy of procalcitonin as a marker in detecting(sepsis in patients with decompensated cirrhosis.)

研究者

发起方
NA
申办方类型
Other [nil]
责任方
Principal Investigator
主要研究者

Dr Ganesh Bhat

Manipal Academy of Higher Education

研究点 (1)

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