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临床试验/ACTRN12609000295246
ACTRN12609000295246已完成4 期

Investigation of Genetic Predictors of the Response to Selective Serotonin Re-Uptake Inhibitors (SSRI) Treatment in individuals suffering from major depression

Tartu University0 个研究点目标入组 135 人开始时间: 2009年5月18日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
135

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomised trial
主要目的
Treatment
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 70 Years(—)
性别
All

入选标准

  • Both genders
  • Major Depression diagnosis according to Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria
  • At severity of depression of at least moderate as indicated by a Montgomery-Asberg's Depression Rating Scale (MADRS) total score of 22 or higher
  • Only secondary current comorbid anxiety disorder

排除标准

  • Bipolar disorder
  • Psychotic disorder or features
  • Current eating disorders
  • Mental retardation
  • Any pervasive developmental disorder or cognitive disorder
  • Alcohol or drug abuse-related disorders within 12 months prior to baseline
  • Acute infections, neurological or any other unstable general disorders, serious suicide risk, formal behaviour therapy, or systematic psychotherapy, pregnancy or breastfeeding
  • A history of hypersensitivity or non-response to escitalopram

研究者

发起方
Tartu University

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