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Clinical Trials/ACTRN12609000295246
ACTRN12609000295246
Completed
Phase 4

Investigation of Genetic Predictors of the Response to Selective Serotonin Re-Uptake Inhibitors (SSRI) Treatment in individuals suffering from major depression

Tartu University0 sites135 target enrollmentMay 18, 2009

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Depression
Sponsor
Tartu University
Enrollment
135
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 18, 2009
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Tartu University

Eligibility Criteria

Inclusion Criteria

  • Both genders
  • Major Depression diagnosis according to Diagnostic and Statistical Manual of Mental Disorders (DSM\-IV) criteria
  • At severity of depression of at least moderate as indicated by a Montgomery\-Asberg's Depression Rating Scale (MADRS) total score of 22 or higher
  • Only secondary current comorbid anxiety disorder

Exclusion Criteria

  • Bipolar disorder
  • Psychotic disorder or features
  • Current eating disorders
  • Mental retardation
  • Any pervasive developmental disorder or cognitive disorder
  • Alcohol or drug abuse\-related disorders within 12 months prior to baseline
  • Acute infections, neurological or any other unstable general disorders, serious suicide risk, formal behaviour therapy, or systematic psychotherapy, pregnancy or breastfeeding
  • A history of hypersensitivity or non\-response to escitalopram

Outcomes

Primary Outcomes

Not specified

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