ACTRN12609000295246
Completed
Phase 4
Investigation of Genetic Predictors of the Response to Selective Serotonin Re-Uptake Inhibitors (SSRI) Treatment in individuals suffering from major depression
Tartu University0 sites135 target enrollmentMay 18, 2009
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Tartu University
- Enrollment
- 135
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Both genders
- •Major Depression diagnosis according to Diagnostic and Statistical Manual of Mental Disorders (DSM\-IV) criteria
- •At severity of depression of at least moderate as indicated by a Montgomery\-Asberg's Depression Rating Scale (MADRS) total score of 22 or higher
- •Only secondary current comorbid anxiety disorder
Exclusion Criteria
- •Bipolar disorder
- •Psychotic disorder or features
- •Current eating disorders
- •Mental retardation
- •Any pervasive developmental disorder or cognitive disorder
- •Alcohol or drug abuse\-related disorders within 12 months prior to baseline
- •Acute infections, neurological or any other unstable general disorders, serious suicide risk, formal behaviour therapy, or systematic psychotherapy, pregnancy or breastfeeding
- •A history of hypersensitivity or non\-response to escitalopram
Outcomes
Primary Outcomes
Not specified
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