Impact of OCT Imaging on Decision Making During PCI in ACS Patients
- Conditions
- Acute Coronary Syndrome
- Interventions
- Device: OCT-guided PCI
- Registration Number
- NCT04444037
- Lead Sponsor
- Assiut University
- Brief Summary
Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.
- Detailed Description
OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 390
- Patients presented with acute coronary syndrome.
- PCI was done to them with stent implantation.
- Multivessel PCI at the index procedure.
- Patients with ACS due to graft failure post CABG.
- Patients treated with no stent implantation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description OCT-guided PCI OCT-guided PCI PCI procedure was done with intra-coronary imaging OCT.
- Primary Outcome Measures
Name Time Method Percent difference in lumen expansion in stent treated lesion Immediately after the procedure Compare residual percent diameter stenosis, percent area stenosis, and acute lumen gain between the two groups.
- Secondary Outcome Measures
Name Time Method Clinical outcomes at 1 year follow up During 1 year following the index procedure Cardiac death, MI, clinical-driven target-lesion revascularization (TLR), and stroke
Trial Locations
- Locations (1)
Wakayama Medical University
🇯🇵Wakayama, Japan