Impact of Optical Coherence Tomography Imaging on Decision-making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Coronary Syndrome
- Sponsor
- Assiut University
- Enrollment
- 390
- Locations
- 1
- Primary Endpoint
- Percent difference in lumen expansion in stent treated lesion
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.
Detailed Description
OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.
Investigators
Amir Khalifa Mahfouz Khalifa
Principle investigator, Cardiology department
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Patients presented with acute coronary syndrome.
- •PCI was done to them with stent implantation.
Exclusion Criteria
- •Multivessel PCI at the index procedure.
- •Patients with ACS due to graft failure post CABG.
- •Patients treated with no stent implantation.
Outcomes
Primary Outcomes
Percent difference in lumen expansion in stent treated lesion
Time Frame: Immediately after the procedure
Compare residual percent diameter stenosis, percent area stenosis, and acute lumen gain between the two groups.
Secondary Outcomes
- Clinical outcomes at 1 year follow up(During 1 year following the index procedure)