Household Air Pollution and Pregnancy Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 307
- 试验地点
- 1
- 主要终点
- Adverse Pregnancy Outcomes
研究概览
简要总结
Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- — 至 35 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women who present to the hospital
- •Who cook exclusively with either kerosene or firewood
- •Before the fourteenth week of pregnancy as determined by ultrasound imaging
排除标准
- •Smoking women or women with smoking family members
- •Women with a high-risk pregnancy defined as:
- •Women with uncontrolled hypertension
- •Women greater than 35 years old carrying their first child
- •Women having triplets or more
- •Women who have had a previous C-section
- •Women carrying babies with fetal abnormalities or as determined by the obstetrician.
结局指标
主要结局
Adverse Pregnancy Outcomes
时间窗: At birth
(first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births.
次要结局
- Reduction in personal exposure to PM2.5, CO and PAH(At birth)