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临床试验/NCT02394574
NCT02394574已完成不适用

Household Air Pollution and Pregnancy Outcome

University of Chicago1 个研究点 分布在 1 个国家目标入组 307 人开始时间: 2012年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
307
试验地点
1
主要终点
Adverse Pregnancy Outcomes

研究概览

简要总结

Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
— 至 35 Years(Child, Adult)
性别
Female
接受健康志愿者

入选标准

  • Pregnant women who present to the hospital
  • Who cook exclusively with either kerosene or firewood
  • Before the fourteenth week of pregnancy as determined by ultrasound imaging

排除标准

  • Smoking women or women with smoking family members
  • Women with a high-risk pregnancy defined as:
  • Women with uncontrolled hypertension
  • Women greater than 35 years old carrying their first child
  • Women having triplets or more
  • Women who have had a previous C-section
  • Women carrying babies with fetal abnormalities or as determined by the obstetrician.

结局指标

主要结局

Adverse Pregnancy Outcomes

时间窗: At birth

(first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births.

次要结局

  • Reduction in personal exposure to PM2.5, CO and PAH(At birth)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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