Household Air Pollution and Pregnancy Outcome

Not Applicable

Completed

• Conditions: Pregnancy
• Interventions: Other: Traditional Cookstove; Other: Clean Cookstove

• Registration Number: NCT02394574
• Lead Sponsor: University of Chicago

Brief Summary

Exposure to Household air pollution (HAP) from burning biomass fuels is responsible for an estimated 2.5 million premature deaths and 3.7% of the loss of disability-adjusted life years (DALY) every year in developing countries.52-54 Of all environmental risks, such as unsafe water, poor sanitation, climate change and lead exposure, HAP accounts for the most mortality and DALY.55 Despite the magnitude of the problems associated with HAP, research on its health effects has been hindered by lack of accurate data on exposure and health outcomes. There are few studies available that report HAP exposures and development of adverse pregnancy outcomes from households using biomass fuels.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2012-09
• Study First Submitted: 2015-03-13
• Study First Submitted QC: 2015-03-17
• Study First Posted: 2015-03-20
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2022-12
• Last Update Submitted: 2024-10-11
• Last Update Posted: 2024-10-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 307

Inclusion Criteria

• Pregnant women who present to the hospital
• Who cook exclusively with either kerosene or firewood
• Before the fourteenth week of pregnancy as determined by ultrasound imaging

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Exclusion Criteria

• Smoking women or women with smoking family members

• Women with a high-risk pregnancy defined as:

  • Women with uncontrolled hypertension
  • Women greater than 35 years old carrying their first child
  • Women having triplets or more
  • Women who have had a previous C-section
  • Women carrying babies with fetal abnormalities or as determined by the obstetrician.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Traditional Cookstove	Traditional Cookstove	Subjects will use traditional firewood or kerosine cookstove and receive education on how to reduce air pollution exposures
Clean Cookstove	Clean Cookstove	Subjects will use ethanol stoves using bioethanol

Primary Outcome Measures

Name	Time	Method
Adverse Pregnancy Outcomes	At birth	(first trimester miscarriages, intrauterine growth retardation, low birth weight (300gm less weight in controls relative to intervention group, premature deliveries (deliveries before 37 weeks of pregnancy) and still births.

Secondary Outcome Measures

Name	Time	Method
Reduction in personal exposure to PM2.5, CO and PAH	At birth	Reduction in personal exposure to PM2.5, CO and PAH in the Ethanol intervention group relative to the control (kerosene/firewood) group

Trial Locations

Locations (1)

College of Medicine. University of lbadan, Ibadan; 🇳🇬 Ibadan, Nigeria