Sputum clearance devices to improve symptoms in chronic obstructive pulmonary disease

Phase 3

Completed

• Conditions: COPD patients who produce sputum regularly; Respiratory

• Registration Number: ISRCTN44651852
• Lead Sponsor: Imperial College, London

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35948418/ (added 12/08/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-30
• Study Completion: 2022-01-14
• Last Update Posted: 2 August 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 103

Inclusion Criteria

Current participant inclusion criteria as of 02/03/2020:
1. Adult patients with COPD who frequently produce sputum defined as: (i) every or most days in the last month and a score of >=5/8 on the two CAT cough items
2. Stable treatment for the preceding four weeks

Previous participant inclusion criteria:
1. Adult patients with COPD who frequently produce sputum defined as: (i) every or most days in the last month and a score of >=6/8 on the two CAT cough items
2. Stable treatment for the preceding four weeks

Exclusion Criteria

1. Unable to provide informed consent
2. Major condition limiting life expectancy for <3 months
3. Referral for chest physiotherapy in the preceding year
4. Already using an adjunct device for sputum clearance
5. Within 1 month of pulmonary exacerbation
6. Within 1 month of COPD medication change
7. Within 1 month of a pneumothorax

Study & Design

• Study Type: Interventional
• Study Design: Not specified