Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents

Not Applicable

Completed

Interventions: Behavioral: Behavioral Activation Therapy app
Behavioral: Treatment as Usual

Brief Summary: The purpose of this study is to evaluate a mobile application (app) called "Goal2QuitVaping" to help adolescents quit vaping nicotine. Goal2QuitVaping was developed by our research team to assist with quitting vaping. Participants will be randomly assigned to either download the mobile app, "Goal2QuitVaping", or not. If provided with Goal2QuitVaping, participants will be asked to use the app regularly, at least once per day, throughout the study duration. Participants will be asked to complete electronic questionnaire measures throughout the study period. Participation in this study will take about 4 weeks.

Recruitment & Eligibility

Inclusion Criteria

age 16-20
vaped nicotine on ≥20 days out of the last 30
elevated depressive symptoms, defined as a score of ≥10 on Patient Health Questionnaire-8 (PHQ-8) during preliminary screening and the Adolescent Patient Health Questionnaire-9 (PHQ-9A) at final eligibility
currently own an iOS or Android smartphone
report willingness to utilize an app for quitting vaping nicotine (response of "yes" on yes/no item)
have a valid e-mail address that is checked regularly or regular access to text messages (for follow-up assessments)
ability to read the consent form
has been seen (in person or remotely) by a primary care physician within the last year

Exclusion Criteria

smoked cigarettes or used other tobacco products on ≥9 days out of the last 30
severe visual impairment
currently receiving treatment for vaping or tobacco use
current suicidal ideation, defined as a response ≥1 on item nine of the PHQ-9A or ≥2 on item 9 of the BDI-II
household member currently enrolled in the study
inability to read the consent form

Arm && Interventions

Group	Intervention	Description
Goal2QuitVaping	Behavioral Activation Therapy app	Participants in the Goal2QuitVaping group will be asked to download the Goal2QuitVaping app to their smartphone. Goal2QuitVaping focuses on mood management as well as on quitting vaping nicotine. Participants will be asked to use Goal2QuitVaping regularly, at least once per day, for the study duration. Participants will also be asked to complete questionnaires weekly for 4 weeks.
Treatment as Usual	Treatment as Usual	Participants in the treatment as usual group will be provided with educational material about quitting vaping nicotine and it will be suggested that they discuss any questions about mood management and about quitting vaping with their primary care provider. The educational material is from the National Cancer Institute's SmokeFree Teen website and includes information on recognizing reasons for quitting vaping, avoiding dual use of e-cigarettes and other tobacco products, setting a quit date, understanding triggers, and accessing social support.

Primary Outcome Measures

Name	Time	Method
Number/Duration of Quit Attempts	Across all 4 weeks	Assessed during the Timeline Followback. Total number of quit attempts across all 4 weeks
Mean Score of Depressive Symptoms	Up to 4 weeks	Patients will self report depressive symptoms weekly for 4 weeks via the Beck Depression Inventory-II. The range of scores possible are 0 - 63, where lower scores are indicative of lower symptoms of depression. This outcome will measure change from baseline at week 4.
Average Vapes Per Day at Week 4	Week 4	Assessed using the Timeline Followback during each weekly assessment. Average vapes per day at week 4.
E-cigarette Dependence	Up to 4 weeks	Assessed at baseline via the 10-item Penn State Electronic Cigarette Dependence Index (ECDI). Change from baseline at week 4. The scores range from 0-20 with 0-3= not dependent, 4-8 low dependence, 9-12 medium dependence, 13+ = high dependence.
7-day Point Prevalence Abstinence	At any point during the study	Assessed during the Timeline Followback. At any point during the study across all 4 weeks.