A study to compare the improvement of hand function in patients suffering from Rheumatoid Arthritis by injecting Depot Methyl Prednisolone either in joints or in muscles.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Patients suffering from Rheumatoid Arthritis for less than 2 years.
- Registration Number
- CTRI/2018/09/015765
- Lead Sponsor
- Institute Of Post Graduate Medical Education And Research SSKM Hospital Kolkata
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
1. Diagnosis of Rheumatoid Arthritis as per ACR/EULAR 2010 classification criteria
2. One or more inflamed joints of hand
3. Duration of disease- less than 2 years
Exclusion Criteria
1. Already deformed joints
2. Uncontrolled Diabetes, hypertension, bleeding diathesis, h/o leprosy, any other
neuropathic disorder
3. Associated fracture or traumatic injury to tendons
4. Open wound or local skin infection
5. Overlap syndromes
6. Who have received intra-articular steroid earlier or is on systemic steroid at time of
presentation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8)Timepoint: Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8):3 months
- Secondary Outcome Measures
Name Time Method 1. Range of motion of joints. <br/ ><br>2. Hand grip measurements. <br/ ><br>3. Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8) <br/ ><br>4. Hand function assessment using Keitel Functional Test. ( parameters 1 to 9)Timepoint: 1. Range of motion of joints:1 month,3 months <br/ ><br>2. Hand grip measurements:1 month,3 months <br/ ><br>3. Patientâ??s disease activity assessment by Clinical Disease Activity Index (CDAI). (0.0-2.8):1 month <br/ ><br>4. Hand function assessment using Keitel Functional Test. ( parameters 1 to 9):1 month,3 months