Optical Coherence Tomography of the Irido-Corneal Angle Before and After Goniotomy and Trabeculotomy in Primary Congenital Glaucoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Central corneal thickness
研究概览
简要总结
The research aimed to improve surgical techniques and long-term outcomes by utilizing this advanced imaging technology to illuminate the structural abnormalities of the anterior segment in eyes with primary congenital glaucoma.
详细描述
Primary congenital glaucoma (PCG) is a rare disease, but it is responsible for 2.5%-15% of all documented cases of pediatric blindness.
The main target of the treatment of pediatric glaucoma is to control the IOP surgically. However, medical treatment could be instituted as a temporary and/or adjunctive option to maximize Intraocular pressure (IOP) control. Initial goniotomy or trabeculotomy have been detected to have high success rates. Trabeculotomy has a comparable long-term success rate in most patients of PCG. The success rate of trabeculotomy is lower in advanced or late-presenting patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Week 至 72 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 1 to 72 weeks.
- •Both sexes.
- •Infants with primary congenital glaucoma.
排除标准
- •Eyes in which the angle could not be visualized by the handheld anterior segment optical coherence tomography (HH AS-OCT).
- •Eyes with previous intraocular surgery.
研究组 & 干预措施
Primary congenital glaucoma group
Infants with primary congenital glaucoma.
干预措施: Optical coherence tomography (Procedure)
结局指标
主要结局
Central corneal thickness
时间窗: 6 months post-procedure
Central corneal thickness was measured using handheld anterior segment optical coherence tomography (HH AS-OCT).
次要结局
- Trabecular-iris angle(6 months post-procedure)
- Iris thickness(6 months post-procedure)
研究者
Maha Mosaad Mohammed Zmetar
Assistant Specialist of Ophthalmology at Ministry of Health of Egypt.
Cairo University