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Special Drug Use-results Survey of Duodopa Enteral Solution in Patients With Parkinson's Disease

Active, not recruiting
Conditions
Parkinson's Disease
Registration Number
NCT02906488
Lead Sponsor
AbbVie
Brief Summary

The purpose of this study is to assess the safety and efficacy of long-term use of Duodopa in patients with Parkinkon's disease in actual usage

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  1. Patients with Parkinson's disease using Duodopa for the purpose of improving circadian change (wearing-off phenomenon) of symptoms of Parkinson's disease in which sufficient effect cannot be obtained with existing drug therapy including levodopa-containing drugs.
Exclusion Criteria

NA

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in "Off" Periods From Start of Treatment to Week 104104 weeks

"Off" periods describe those times when medication is not working well and a person has greater difficulty with movement.

Secondary Outcome Measures
NameTimeMethod
Time-dependent Change in Parkinson's Disease Questionnaire - 8 Items (PDQ-8)104 weeks

The PDQ-8 is a quality of life questionnaire for PD patient. This short-form version derived from the PDQ-39 includes 1 question from each of the domains on the PDQ-39 (mobility, ADLs, emotional well-being, stigma, social support, cognitions, communication, and bodily discomfort).

"Off" Period and "On" Period Accompanied by Dyskenesia Interfering with Daily Activities by Patient Characteristic Factor104 weeks

"Off" periods describe those times when medication is not working well and a person has greater difficulty with movement, and "On" periods describe when medication is working well and symptoms are controlled.

Time-dependent Change in Unified Parkinson's Disease Rating Scale (UPDRS)104 Weeks

Motor evaluation

Time-dependent Change in "Off" Time and "On" Time Accompanied By Dyskinesia Interfering with Daily Activities104 Weeks

"Off" periods describe those times when medication is not working well and a person has greater difficulty with movement, and "On" periods describe when medication is working well and symptoms are controlled.

Time-dependent Change in Parkinson's Disease Quality of Life Questionnaire - Carers (PDQ-Carer)104 weeks

The PDQ-Carer is a 29 item measure of health related quality of life for use with carers of people with Parkinson's disease.

Trial Locations

Locations (115)

Nagoya City University Hospital /ID# 166893

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Nagoya shi, Aichi, Japan

Nagoya University Hospital /ID# 212303

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Nagoya-shi, Aichi, Japan

Toyota Memorial Hospital /ID# 166891

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Toyota-shi, Aichi, Japan

Akita City Hospital /ID# 207121

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Akita-shi, Akita, Japan

National Hospital Organization Akita National Hospital /ID# 207374

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Yurihonjo-shi, Akita, Japan

Aomori Prefectural Central Hospital /ID# 165286

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Aomori-shi, Aomori, Japan

Kameda General Hospital /ID# 166906

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Kamogawa-shi, Chiba, Japan

Juntendo University Urayasu Hospital /ID# 162890

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Urayasu-shi, Chiba, Japan

Saiseikai Matsuyama Hospital /ID# 169561

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Matsuyama-shi, Ehime, Japan

Saiseikai Saijo Hospital /ID# 167705

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Saijo-shi, Ehime, Japan

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Nagoya City University Hospital /ID# 166893
🇯🇵Nagoya shi, Aichi, Japan

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