Investigating the effect of vitamin A ophthalmic ointment on reducing pain after refractive keratectomy surgery

Phase 3

Recruiting

Conditions: Pain reduction after Photorefractive keratectomy surgery.

Registration Number: IRCT20240213060989N1

Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 56

Inclusion Criteria

Class I and II of the American Society of Anesthesiology
People with refractive error myopia and regular astigmatism (both together or each one alone)
The optical amount of the zone is 5.6 - 5.7
People with spherical equivalent maximum 3.5 diopters

Exclusion Criteria

Lack of consent to participate in the study
Use of contact lenses in the last two months
Presence of corneal scratch before surgery
taking medication
Corneal dystrophies
The presence of any structural disorder of the eye
Pathology and eye diseases
Existence of systemic diseases (diabetes, vascular collagen disorder, etc.)
People with hyperopia, amblyopia

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale (VAS). Timepoint: Immediately after the operation, 6, 12 and 24 hours. Method of measurement: It will be quantitatively recorded from 0 (no pain) to 5 (very intense pain that is excruciating).

Secondary Outcome Measures

Name	Time	Method
Corneal scratch. Timepoint: Examination by hand-held slit lamp In the daily visits after the surgery (until the complete recovery of the corneal scratch) and then a re-visit will be done one week after the surgery. Method of measurement: Based on mm.;Time of onset of first pain. Timepoint: Based on the patient condition checklist. Method of measurement: Time of onset of first pain after surgery.;Patient's eye complaint. Timepoint: Based on the patient condition checklist. Method of measurement: subjectively and comparing binoculars.