Database: Standardized Prenatal Management and Perinatal Outcome of Complicated Monochorionic Pregnancies
Overview
- Phase
- Not Applicable
- Intervention
- Monochorionic Pregnancy Group
- Conditions
- Monochorionic Diamniotic Placenta
- Sponsor
- University of Miami
- Enrollment
- 1200
- Locations
- 1
- Primary Endpoint
- Number of participants with Preterm Delivery
- Status
- Active, not recruiting
- Last Updated
- 2 months ago
Overview
Brief Summary
The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.
Investigators
Rodrigo Ruano
Professor and Chief of MFM Division
University of Miami
Eligibility Criteria
Inclusion Criteria
- •The study population will consist of MC pregnancies (maternal, fetal, and neonatal data) that have undergone evaluation and/or treatment for complications attributable to monochorionic twin pregnancy at the University of Miami.
- •Maternal age 18 years and older.
Exclusion Criteria
- •Participation declined or consent not granted in prospective arm
- •Loss to follow-up
Arms & Interventions
Monochorionic Pregnancy Group
Participants with complicated monochorionic pregnancies (MC) will be followed prospectively beginning at the time of the mother's evaluation for a complication related to monochorionic (MC) multiple pregnancies through delivery of the child and follow-up of the child to 12 months of life.
Outcomes
Primary Outcomes
Number of participants with Preterm Delivery
Time Frame: Up to 42 weeks gestation
Preterm delivery is defined as birth \<37 weeks gestation
Number of participant with Premature Spontaneous Rupture of the Membranes
Time Frame: Up to 42 weeks
As per clinical evaluation
Number of Infant Deaths
Time Frame: Up to 12 months post infant delivery
The Number of Infant Deaths