Prognostic impact of serum concentrations of NSE and S-100 in patients after cardiac surgery due to type A aortic dissectio
Recruiting
- Conditions
- T82Dissection of aorta [any part]Complications of cardiac and vascular prosthetic devices, implants and graftsI71.0
- Registration Number
- DRKS00028926
- Lead Sponsor
- niklinikum Regensburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
type A aortic dissection, that needs to be treated
Exclusion Criteria
preoperative resuscitation due to this dissection/ no letter of acceptance
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Is there a correlation of the postoperative NSE- and Protein S-100-levels, which will be taken for five days after the surgery, and the neurological outcome of the patient at the day he gets discharged of hospital? The neurological outcome will be evaluated with a SIDAM-test. The test will be taken the same day the patient will be discharged.
- Secondary Outcome Measures
Name Time Method Could the establishment of NSE and/or Protein S-100 serve as a predictive marker in cases of surgical intervention of type A aortic dissection?
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways link NSE and S-100 biomarkers to neurologic complications in type A aortic dissection post-surgery?
How do serum NSE and S-100 levels compare to standard biomarkers in predicting mortality after aortic dissection repair?
Which patient subgroups with type A aortic dissection show elevated NSE/S-100 concentrations and worse outcomes in observational studies?
What adverse neurologic events correlate with NSE/S-100 elevation in cardiac surgery for acute aortic dissection (I71.0)?
Are NSE and S-100 validated as early prognostic indicators in aortic dissection management at niklinikum Regensburg?