Iron Overload in Stem Cell Transplant Recipients
Completed
- Conditions
- Iron Overload
- Registration Number
- NCT00806715
- Lead Sponsor
- Boston Children's Hospital
- Brief Summary
The goal of this study is to examine the impact of iron overload in patients undergoing a bone marrow transplant. We believe that the iron status in these patients is associated with complications for transplant survivors. We will examine the iron status in these patients by MRI and by screening for mutations in genes known to cause iron overload. We will also determine the levels of hepcidin (a hormone produced in the liver that appears to regulate iron homeostasis) from blood and urine.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hepatic iron content as measured by R2 MRI. Pre-HSCT and Day 100
- Secondary Outcome Measures
Name Time Method Genetic determinants of iron overload- HFE status. Pre-HSCT
Trial Locations
- Locations (1)
Children's Hospital Boston
🇺🇸Boston, Massachusetts, United States