The effect of endoscopic sinus surgery on improvement of olfaction in chronic rhinosinusitis patients

Phase 3

• Conditions: J31.0, J32; Chronic Rhinitis, Chronic Sinusitis; Chronic Rhinosinusitis.

• Registration Number: IRCT2017050517413N24
• Lead Sponsor: Vice Chancellor for Research, Baqiyatallah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients between 18 and 65 years of age; no response to standard medical treatment with nasal irrigation by normal saline (4 times daily), nasal corticosteroid Fluticasone (one puff daily) and antibiotic therapy by Cefixime (400 mg daily) for 4 weeks

Exclusion criteria: Head trauma; Smoking; prior other treatments

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Olfactory threshold. Timepoint: Before, one month and three months after interventin. Method of measurement: Smell Threshold Test.

Secondary Outcome Measures

Name	Time	Method
Drug Complications. Timepoint: During study. Method of measurement: Patients' complaint.;Surgical Complications. Timepoint: After surgery. Method of measurement: Examination and patients' complaints.