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Does Vestibular System Effected in Chronic Obstructive Pulmonary Disease Patients

Not yet recruiting
Conditions
Vestibular Disorder
Interventions
Other: Respiratory Assessment
Other: Vestibular Assessment
Other: Balance Assessment
Registration Number
NCT04280211
Lead Sponsor
Nimet Sermenli Aydın
Brief Summary

. The main question is whether the vestibular system is affected by COPD. If there is an influence, the second question is what is the relationship between balance and vestibular interaction in COPD patients. A total of 10 COPD patients and 10 healthy adults will include the study. Respiratory functions, vestibular functions and postural stability of participants will be assessed. This research is planned to be carried out as a cross-sectional/descriptive research. It's planned as a pilot study. Comparisons between study and control groups will be made with independent samples t-test for parametric values and Mann Whitney U for non-parametric values.

Detailed Description

Chronic Obstructive Pulmonary Disorder (COPD) is a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Hypoxia caused by restrictive airflow is one of the symptoms of COPD. Hypoxia can affect the inner ear and vestibular nuclei. Also, balance impairment can be caused by hypoxia. Previous studies show that balance affected negatively in COPD patients. The aim of this study is to investigate of vestibular system influence in individuals with COPD. A total of 10 COPD patients and 10 healthy adults will include the study. This research is planned to be carried out as a cross-sectional/descriptive research. It's planned as a pilot study. Respiratory functions (respiratory function test), vestibular functions (head shake test, head trust test, unterberger test) and postural stability (sensory organization test) of participants will be assessed.Comparisons between study and control groups will be made with independent samples t-test for parametric values and Mann Whitney U for non-parametric values.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Volunteering to participate in the study
  • Diagnosed with COPD
Exclusion Criteria
  • Communication - Coordination problems of patients
  • Using medicine which is increasing the risk of fall
  • Any neurologic or musculoskeletal disorders which affect mobility and balance
  • Loss of hearing

For control group

Inclusion Criteria:

  • Volunteering to participate in the study

Exclusion Criteria:

  • Communication - Coordination problems of patients
  • Using medicine which is increasing the risk of fall
  • Any neurologic, musculoskeletal or respiratory disorders which affect mobility and balance
  • Loss of hearing

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Control GroupRespiratory AssessmentHealthy adults over 40 years old
Control GroupBalance AssessmentHealthy adults over 40 years old
Control GroupVestibular AssessmentHealthy adults over 40 years old
COPD GroupRespiratory AssessmentPatients who are over 40 years old, diagnosed with COPD
COPD GroupVestibular AssessmentPatients who are over 40 years old, diagnosed with COPD
COPD GroupBalance AssessmentPatients who are over 40 years old, diagnosed with COPD
Primary Outcome Measures
NameTimeMethod
Vestibular Assessment 1After the individuals permission, in first 4 minutes

Head Shake Test:The head shake test is performed by shaking the head of the patient. The head is rotated at a comfortable range at a frequency of about 2 to 3 Hertz for 10- to 15 seconds. After shaking, the head remains in the center and the eyes of the patient are observed for nystagmus. The head shake test is used to look for signs of dynamic imbalance of vestibular function by evaluating the post-shaking nystagmus.

Balance AssessmentAfter the individuals permission, in first 20 minutes

Subjects stands on dual force plates and and their anterior posterior sway recorded in different test conditions.

1. Eyes open- stable support

2. Eyes closed- stable support

3. Eyes open- stable support

4. Eyes open-Foam surface

5. Eyes closed-Foam surface

6. Eyes open-Foam surface

Respiratory Assessment - Spirometry - Forced expiratory volume in 1 s (FEV1)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

Forced expiratory volume in 1 s (FEV1)

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Respiratory Assessment - Spirometry - Forced vital capacity (FVC)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

FVC, the maximum amount of air that can be exhaled when blowing out as fast as possible

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Respiratory Assessment - Spirometry - Vital capacity (VC)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

Vital capacity (VC), the maximum amount of air that can be exhaled when blowing out as fast as possible

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Respiratory Assessment - Spirometry - Peak expiratory flow (PEF)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

Peak expiratory flow (PEF), the maximal flow that can be exhaled when blowing out at a steady rate

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Respiratory Assessment - Spirometry - Forced expiratory flow (FEF)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

Forced expiratory flow, also known as mid-expiratory flow; the rates at 25%, 50% and 75% FVC are given

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Respiratory Assessment - Spirometry - •Inspiratory vital capacity (IVC)After the individuals permission, in first 22 minutes

\*We will supply the information of test results from patients' folders.\*

Inspiratory vital capacity (IVC), the maximum amount of air that can be inhaled after a full expiration

Spirometry is the term given to the basic lung function -volume, time and flow- tests that measure the air that is expired and inspired. Spirometry is objective and noninvasive.

Before performing the forced expiration, tidal (normal) breaths can be taken first, then a deep breath taken in while still using the mouthpiece, followed by a further quick, full inspiration.

Vestibular Assessment 2After the individuals permission, in first 8 minutes

Head Trust Test: A brief, high-acceleration head thrust can test vestibular function of all semicircular canals. Depending on the semicircular canal tested, the head is rotated in a different direction. A corrective catch-up saccade is made in case of vestibular hypofunction.

Vestibular Assessment 3After the individuals permission, in first 10 minutes

Unterberger test: Subjects will close their eyes and begin stepping in place for 60 seconds with shoulder at 90 degrees flexion, arms extended forward. The distance will be measured from the start point to end point.

Secondary Outcome Measures
NameTimeMethod
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