The effect of simultaneous supplementation of oral vitamin D and intravenous vitamin C on inflammatory indices, oxidative stress and clinical outcomes in patients with acute respiratory failure admitted to the intensive care unit

Iran University of Medical Sciences0 个研究点目标入组 64 人开始时间: 待定最近更新: 2023年8月21日

试验速览

暂无简介。

•hospitalized patients in the intensive care unit
•suffering from acute respiratory failure (PaO2 = 60 mmHg or PaCO2 > 45 mmHg)
•not Suffering from a nervous system disease that prevents the patient from being separated from the mechanical ventilation device
•not suffering from AIDS
•not suffering from Liver failure
•not Suffering from kidney diseases including nephrotic syndrome-
•not suffering from gout
•not being Pregnancy and breastfeeding
•Vitamin D level below 50 ng/mL
•not suffering from hypercalcemia (total calcium > 10.6 mg/dL)
•not Suffering from hyperphosphatemia (> 1.45 mmol/liter)
•not suffering from Tuberculosis
•not suffering from sarcoidosis
•not Passing more than 24 hours from the diagnosis of the disease to the time of entering the study
•not participating in other interventional studies in the last 30 days
•not consuming vitamin D and vitamin C supplements in the last 30 days

•Death or hospitalization of the patient less than 3 days from the start of the intervention
•Unwillingness to continue studying and cooperating in it
•developing contraindications for the administration of vitamin D and vitamin C according to the opinion of the attending physician at the time of the study.

发起方