Major Adverse Cardiac Events After Carotid Endarterectomy

Completed

• Conditions: Carotid Stenosis; Carotid Endarterectomy; Adverse Cardiac Events

• Registration Number: NCT03596229
• Lead Sponsor: Mahidol University

Brief Summary

Carotid endarterectomy is the operation for curing the significant carotid artery stenotic patients who are also at high cardiac risk. This retrospective study is to find out the incidence and risk factors related.

Detailed Description

The investigator plan to retrospectively investigate 175 carotid endarterectomy patients in Siriraj hospital to find the incidences of major adverse cardiac events, including

* Myocardial infarction is defined as rising of cardiac bio-markers in the setting of myocardial ischemia (Relevant anginal symptoms, ECG changes or Imaging e.g. Echocardiography)2,10

* Significant arrhythmia is defined as symptomatic or causing hemodynamic changes without other explainable causes.

* Heart failure is defined according to Modified Framingham criteria3

* Cardiac death is defined as mortality in association and as a direct result from myocardial infarction, arrhythmia or heart failure

if possible, the investigators will try to find the associate or risk factors for those events.

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study First Submitted: 2018-07-05
• Study First Submitted QC: 2018-07-20
• Study First Posted: 2018-07-23
• Study Start: 2018-10-01
• Primary Completion: 2019-11-30
• Status Verified: 2020-01
• Study Completion: 2020-01-15
• Last Update Submitted: 2020-01-17
• Last Update Posted: 2020-01-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 175

Inclusion Criteria

• Every patients undergoing carotid endarterectomy in Siriraj hospital

Read More

Exclusion Criteria

• Patients with other simultaneous surgery with carotid endarterectomy

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of major adverse cardiac events after carotid endarterectomy	7 days	Major adverse cardiac event included myocardial infarction, significant arrhythmia, heart failure and cardiac arrest

Secondary Outcome Measures

Name	Time	Method
other adverse events	7 days	respiratory complications, such as re-intubation, aspiration Neurologic complication, such as stroke length of hospital stay, ICU admission, length of ICU stay
associate factors with adverse cardiac event	7 days	Analysis of potential factors associated with major adverse cardiac event after carotid endarterectomy

Trial Locations

Locations (1)

Faculty of Medicine Siriraj Hospital; 🇹🇭 Bangkok, Thailand