Screening study of mismatch repair (MMR) protein and BRAF mutant protein for rectal cancer
Not Applicable
- Conditions
- Rectal cancer confirmed by histopathological diagnosis
- Registration Number
- JPRN-UMIN000050759
- Lead Sponsor
- ational Cancer Center Hospital East
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 1000
Inclusion Criteria
Not provided
Exclusion Criteria
1)Cases judged to be unsuitable for enrollment in this study. 2)Patients who have requested that they do not wish to participate in the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of dMMR in rectal cancer specimens, loss of expression frequency of each MMR protein (MLH1, PMS2, MSH2, MSH6), frequency of BRAF V600E mutation
- Secondary Outcome Measures
Name Time Method Associations between MMR, BRAF V600E mutation status and patient background factors