Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement
- Conditions
- Chronic Rhinosinusitis
- Interventions
- Other: Early saline irrigationOther: Routine Irrigation
- Registration Number
- NCT01943370
- Lead Sponsor
- University of Alberta
- Brief Summary
Nasal saline is a common treatment adjunct in the post-operative setting for endoscopic sinus surgery. However, the ideal timing and quantity of irrigation in the early post-operative period remains unknown. Proposed benefits of early, large volume irrigation include removal and softening of crusts, resulting in improved mucociliary clearance. The potential benefit of early large volume saline irrigation on post-operative day three to ease or reduce the need for early post-operative debridement has not been studied.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
- Adult patients
- Diagnosis of CRS with or without polyposis
- Undergoing bilateral endoscopic sinus surgery
- Availability of pre-operative CT paranasal sinuses
Patients with diagnosis of:
- Primary ciliary dyskinesia
- Immunodeficiency
- Cystic fibrosis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Late or Routine Saline Irrigation Early saline irrigation Routine initiation of saline irrigation Early saline irrigation Early saline irrigation Initiation of early saline irrigation Late or Routine Saline Irrigation Routine Irrigation Routine initiation of saline irrigation
- Primary Outcome Measures
Name Time Method Pain Early post-operative (Day 10) Pain and discomfort during early post-operative debridement on post-operative day 10
- Secondary Outcome Measures
Name Time Method Endoscopic appearance Early (post-operative day 10) Early post-operative POSE score on post-operative day 10
Late endoscopic appearance at 6 months 6 months Late post-operative endoscopic POSE score at 6 months