Early Saline Irrigation to Decrease Post-operative Endoscopic Debridement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 主要终点
- Pain
研究概览
简要总结
Nasal saline is a common treatment adjunct in the post-operative setting for endoscopic sinus surgery. However, the ideal timing and quantity of irrigation in the early post-operative period remains unknown. Proposed benefits of early, large volume irrigation include removal and softening of crusts, resulting in improved mucociliary clearance. The potential benefit of early large volume saline irrigation on post-operative day three to ease or reduce the need for early post-operative debridement has not been studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 17 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients
- •Diagnosis of CRS with or without polyposis
- •Undergoing bilateral endoscopic sinus surgery
- •Availability of pre-operative CT paranasal sinuses
排除标准
- •Patients with diagnosis of:
- •Primary ciliary dyskinesia
- •Immunodeficiency
- •Cystic fibrosis
研究组 & 干预措施
Early saline irrigation
Initiation of early saline irrigation
干预措施: Early saline irrigation (Other)
Late or Routine Saline Irrigation
Routine initiation of saline irrigation
干预措施: Early saline irrigation (Other)
Late or Routine Saline Irrigation
Routine initiation of saline irrigation
干预措施: Routine Irrigation (Other)
结局指标
主要结局
Pain
时间窗: Early post-operative (Day 10)
Pain and discomfort during early post-operative debridement on post-operative day 10
次要结局
- Endoscopic appearance(Early (post-operative day 10))
- Late endoscopic appearance at 6 months(6 months)
研究者
Caroline Xu
Resident
University of Alberta