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临床试验/CTRI/2023/01/049323
CTRI/2023/01/049323尚未招募不适用

CLINICAL PROFILE OF NEONATES WITH RESPIRATORY DISTRESS IN TERTIARY CARE CENTRE:"A CROSS SECTIONAL STUDY"

Rohilkhand Medical College and Hospital Bareilly UP1 个研究点 分布在 1 个国家目标入组 144 人开始时间: 2023年5月2日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
144
试验地点
1
主要终点
To determine the various etiology of the respiratory distress in neonates

研究概览

简要总结

First breath is the most vital parameter in the beginning of a new life. Respiratory distress is a challenging problem and one of the most common cause of admission for neonatal intensive care unit (NICU) in both term and preterm infants1. Most of the causes of neonatal morbidity and mortality are preventable. Incidence of respiratory distress depends on various factors like gestational age, low birth weight, perinatal infections, and complications during pregnancy2. In a neonate, clinical diagnosis of respiratory distress is suspected if the respiratory rate is greater than 60 per minute in a quite resting baby, presence of grunting and/or there are inspiratory subcostal/intracostal retractions3. Presence of grunting, nasal flaring, retractions, tachypnea, decreased breath sounds are the important signs of respiratory distress4. Even in healthy term infants, oxygenation is impaired immediately after birth, and oxygen saturation gradually increases and exceeds 90% only at about 5 min5.

The severity of respiratory distress can be assessed by Downe’s scoring system6 and Silverman Anderson scoring system7. Respiratory distress syndrome, transient tachypnea of neonate, pneumonia, pneumothorax and air leaks, congenital pneumonia, Meconium aspiration syndrome, Tracheo-esophageal fistula, Diaphragmatic hernia are the important causes of respiratory distress in neonates8.

1

Other uncommon respiratory causes include congenital lobar emphysema, accessory or

研究设计

研究类型
Observational

入排标准

年龄范围
1.00 Day(s) 至 28.00 Day(s)(—)
性别
All

入选标准

  • Neonates with respiratory distress who were admitted in NICU within 28 days of life.
  • Neonates whose parents are willing to give consent.

排除标准

  • Neonates born with chromosomal disorders admitted to NICU.
  • Neonates born with inborn metabolic disorders admitted to NICU.

结局指标

主要结局

To determine the various etiology of the respiratory distress in neonates

时间窗: 1 week

次要结局

  • To study the spectrum of initial clinical presentation, progression and recovery of the respiratory distress with respect to scoring system.(1 week)

研究者

发起方
Rohilkhand Medical College and Hospital Bareilly UP
申办方类型
Private medical college

研究点 (1)

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