The feasibility of continuous positive airway pressure ventilation in acute ischemic stroke patients: a pilot study

Completed

• Conditions: ischemic stroke; cerebral infarction; 10007963; 10046304

• Registration Number: NL-OMON48215
• Lead Sponsor: OLVG

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

* 18 years and older
* First-ever AIS (onset < 4.5hours)

Exclusion Criteria

* Medical history of IS
* Medical history of OSA
* Hemorrhagic stroke
* TIA

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary endpoint is feasibility defined as CPAP compliance during the<br /><br>study period. Compliance is expressed as the average use of CPAP per night<br /><br>measured by a memory card integrated in the CPAP device. Good compliance will<br /><br>be defined as an average usage of more than 4 hoursper night.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints:<br /><br>- Inclusion rate<br /><br>- Adverse events (AE): CPAP related AEs<br /><br>- Percentage of withdrawal from CPAP treatment<br /><br>- Self-evaluation of CPAP by patients and their caregivers<br /><br>- Functional status: The National Institutes of Health Stroke Scale (NIHSS) and<br /><br>modified Rankin Scale (mRS)<br /><br>- Cognitive status: Montreal Cognitive Assessment (MoCA) and Trail Making Test<br /><br>(TMT)<br /><br>- OSA prevalence measured by polysomnography (PSG)<br /><br>- Epworth Sleepiness Scale (ESS)</p><br>