Effects of long-term resveratrol supplementation on metabolic health

Completed

Conditions: obesitas and sugar disease
10018424
10013317

Registration Number: NL-OMON44710

Lead Sponsor: niversiteit Maastricht

Brief Summary: Trial is onging in other countries

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 42

Inclusion Criteria

* Men aged 40-70 years and postmenopausal women aged 50-70 years
* BMI: 27-35 kg/m2
* Stable dietary habits: no weight gain or loss > 5kg in the last three months
* Willingness to limit consumption of resveratrol-containing food products and willingness to refrain from using resveratrol containing supplements
* Subjects will only be included when the dependent medical doctor of this study approves participation after evaluating data obtained during screening

Exclusion Criteria

* Uncontrolled hypertension
* HbA1c > 6.5%
* Previously diagnosed with type 2 diabetes
* Medication use known to interfere with glucose homeostasis/metabolism
* Current alcohol consumption > 20 grams alcohol/day
* Subjects who do not want to be informed about unexpected medical findings during the screening /study, or do not wish that their physician is informed, cannot participate in the study.
* Participation in another biomedical study within 1 month before the start of the intervention
* Any condition, disease or abnormal laboratory test result that, in the opinion of the Investigator, would interfere with the study outcome, affect trial participation or put the subject at undue risk

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The most important study parameters are differences in: glucose tolerance,<br /><br>resting energy expenditure, intra-hepatic lipid content, body composition and<br /><br>blood plasma values</p><br>

Secondary Outcome Measures