Predictive Model of Mortality and Major Morbidity in Preterm Neonates in the Perinatal Period (Survival Model)
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Mortality
- Sponsor
- Cardiff and Vale University Health Board
- Enrollment
- 5000
- Locations
- 1
- Primary Endpoint
- Mortality or major morbidity
- Status
- Not Yet Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Study Title Predictive Model of Mortality and Major Morbidity in Preterm Neonates in the Perinatal Period Internal ref. no. / short title Survival Model Study Design Observational Population-based Cohort Study Planned Sample Size Retrospective analysis of Database Planned Study Duration 6-months Primary Objectives To derive a mathematical model for predicting mortality and the composite of mortality/major-morbidity before and immediately after birth in preterm infants Secondary Objectives Statistical Methodology and Analysis Mixed-model multivariable logistic regression analysis
Investigators
Eligibility Criteria
Inclusion Criteria
- •Preterm infants born alive at or less than 34 weeks of gestation.
- •Born in Welsh maternity and admitted for care to a Welsh neonatal unit.
- •Mother normally resident in Wales
- •Exclusion Criteria
- •The mother is normally resident in England (detailed maternal data not available)
- •Congenital anomaly noted at birth (alters the natural probability of outcomes)
- •Duplicate episodes for an individual infant
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Mortality or major morbidity
Time Frame: 40-weeks
In-hospital outcomes
Mortality
Time Frame: 40-weeks
In-hospital mortality