Laser Assisted Sperm Selection of Viable Immotile Testicular Sperm in Azoospermic Infertile Men
Not Applicable
Completed
- Conditions
- AzoospermiaIVF
- Interventions
- Procedure: Hypo-osmotic Swelling TestDevice: Laser Assisted Immotile Sperm Selection
- Registration Number
- NCT04675164
- Lead Sponsor
- Sohag University
- Brief Summary
This study aims to investigate the outcome of ICSI after using LAISS for selection of viable immotile testicular sperm in azoospermic infertile men.
Patients will be randomly assigned to 2 groups. In (LAISS) group, viable immotile testicular sperms will be selected before ICSI using laser assisted immotile sperm selection (study group). In (HOST) group, viable immotile testicular sperms will be selected before ICSI using hypo-osmotic swelling test (control group).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 168
Inclusion Criteria
- Eligible couples are those undergoing ICSI due to azoospermia with testicular biopsy positive for sperm (either fresh or cryopreserved) following testicular sperm extraction (TESE) or aspiration (TESA).
Exclusion Criteria
- Cases with female factor infertility or woman age above 35 years will be excluded.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description HOST group Hypo-osmotic Swelling Test Viable immotile testicular sperms will be selected before ICSI using hypo-osmotic swelling test (control group). LAISS group Laser Assisted Immotile Sperm Selection Viable immotile testicular sperms will be selected before ICSI using laser assisted immotile sperm selection (study group).
- Primary Outcome Measures
Name Time Method Clinical pregnancy rate 6- 7 weeks Presence of a fetal heartbeat at 6-7 weeks of pregnancy.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ajyal Hospital, IVF Center
🇪🇬Sohag, Egypt