跳至主要内容
临床试验/NCT02745249
NCT02745249已完成不适用

Assessing the Feasibility of Integrating Maternal Nutrition Interventions Into an Existing Maternal, Newborn, and Child Health Platform in Bangladesh: A Cluster-randomized Operational Evaluation

International Food Policy Research Institute2 个研究点 分布在 1 个国家目标入组 3,500 人开始时间: 2015年7月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
3,500
试验地点
2
主要终点
Use of iron-folic acid supplements

研究概览

简要总结

Inadequate maternal nutrition is likely to undermine the potential impact of infant and young child feeding (IYCF) improvements made in the Alive & Thrive (A&T) first phase because it is linked to poor fetal growth leading to small-for-gestational age and pre-term newborns. These babies do not respond to growth promoting feeding practices as well as normal newborns do. In Phase 2, Alive & Thrive decided to focus on integrating a package of maternal nutrition interventions in a large-scale maternal, newborn and child health program (MNCH). This proposed evaluation aims to assess the feasibility of integrating maternal nutrition interventions into an existing MNCH platform in Bangladesh, using a cluster-randomized evaluation design.

详细描述

Inadequate maternal nutrition is likely to undermine the potential impact of IYCF improvements made in the Alive & Thrive (A&T) first phase because it is linked to poor fetal growth leading to small-for-gestational age and pre-term newborns. These babies do not respond to growth promoting feeding practices as well as normal newborns do (WHO Healthy Growth project). In a study of 16,290 singleton infants born in rural Bangladesh from 2004 to 2007, more than 50% were born with low birth-weight. Low birth-weight is a risk factor for neonatal deaths, estimated to be 37 per 1,000 live births in Bangladesh. Factors associated with low birth-weight include young maternal age, poor pre-pregnant nutritional status, short birth intervals, poor maternal dietary intake (quality, quantity, and diversity), and inadequate pregnancy weight gain. Better maternal nutrition will improve maternal and newborn outcomes and facilitate achievement of a continuum of good nutrition.

In setting its country program goal for Bangladesh in phase 2, Alive & Thrive decided to focus on demonstrating the feasibility of integrating a package of maternal nutrition interventions in a large-scale MNCH program. Maternal nutrition should receive equal priority as child nutrition and the A&T program of BRAC already has developed an effective strategy though improving IYCF practices. MNCH programs offer the best opportunity for achieving large scale and sustainability. The GOB also promotes mainstreaming of nutrition intervention in health services. Considering the behavior change focus of the Alive & Thrive strategy, efforts will concentrate on improving dietary practices, specifically, improved diversity of foods and energy intakes of pregnant women, and improve the intake of calcium and iron/folic acid supplements. BRAC's supply system will be used to ensure access to calcium and iron/folic acid supplements. The current Government of Bangladesh guidelines of supplementing pregnant women with iron and folic acid and calcium, taken with food (to minimize adverse effects) would be a focus of behavior change interventions.

The primary objectives of the proposed evaluation are to answer the following questions using a cluster-randomized evaluation design:

  • Can the coverage and utilization of key maternal nutrition interventions be improved equitably by integrating nutrition-focused BCC and community mobilization into BRAC's rural MNCH program?
  • What factors affect high quality integration of nutrition interventions into a well-established MNCH program platform?

Secondary objectives are to examine the following question:

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Recently delivered women with children <6 months of age
  • Pregnant women in second and third trimester and her husbands
  • Frontline health workers in the areas

排除标准

  • Mental disorders that cannot understand and answer the questions

研究组 & 干预措施

A&T- intensive

Experimental

A&T-intensive arm receive standard MNCH services and intensified maternal nutrition behavior change intervention which focus on improving dietary practices, specifically improved diversity of foods and energy intakes of pregnant women, and improved intake of calcium and iron/folic acid (IFA) supplements.

干预措施: Maternal Nutrition Behavior change (Behavioral)

A&T-non intensive

No Intervention

A&T-non intensive aim only receive MNCH services

结局指标

主要结局

Use of iron-folic acid supplements

时间窗: IFA tablets used during 9 months of last pregnancy among recently delivered women with children <6 months of age by June 2016

Recall the total number of IFA tablets consumed throughout the last pregnancy

Use of calcium supplements

时间窗: Calcium tablets used during 9 months of last pregnancy among recently delivered women with children <6 months of age by June 2016

Recall the total number of calcium tablets consumed throughout the last pregnancy

Dietary micronutrient intakes

时间窗: Pregnant women in second and third trimester of pregnancy (4-9 months) by June- August 2016

Quantity of micronutrient intakes using 24-hour recall complemented by food weighing.

Dietary diversity during pregnancy

时间窗: Pregnant women in second and third trimester of pregnancy (4-9 months) by June- August 2016

Number of food groups women consumed

Coverage of maternal nutrition intervention

时间窗: 1 year

The proportion of pregnant and recently delivery women expose to and use of MNCH platform during the last 1 year

次要结局

  • Early initiation of breastfeeding(Infants up to 6 months in a cross-sectional endline survey scheduled for June- August 2016)
  • Exclusive breastfeeding(Infants up to 6 months in a cross-sectional endline survey scheduled for June- August 2016)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验

Assessing the Feasibility of Integrating Maternal... | 临床试验