NCT03708627招募中1 期
The Role of Bimatoprost in Graves' Periorbitopathy
Johns Hopkins University1 个研究点 分布在 1 个国家目标入组 3 人开始时间: 2017年11月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 3
- 试验地点
- 1
- 主要终点
- Reduction in periorbital fat causing improvement in proptosis
研究概览
简要总结
Testing whether Bimatoprost, a topical eye drop used for glaucoma, can be used to induce periorbital fat atrophy in patients with Graves' disease
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcomes assessor will evaluate clinical photos. Other measures such as Hertel's exophthalmometry values are objective outcomes which will be made available to the Principal Investigator
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Graves' Ophthalmopathy with Exophthalmos/Proptosis -
排除标准
- •Active Graves Disease, Currently pregnant, Taking Steroids
研究组 & 干预措施
Bimatoprost in more proptotic eye
Experimental
Patients instill Bimatoprost in their more proptotic eye one nightly
干预措施: Bimatoprost Ophthalmic (Drug)
结局指标
主要结局
Reduction in periorbital fat causing improvement in proptosis
时间窗: 1 year
次要结局
未报告次要终点
研究者
研究点 (1)
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