Gentamicin intratympanic injection concurrent with dexamethasone in refractory Meniere’s disease.
Not Applicable
Recruiting
- Conditions
- Diseases of the ear and mastoid process
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Definite Meniere’s disease
-If there is no improvement in medication treatment for more than 3 months and there is more than 1 dizziness attack per month
-The average hearing on the affected side is more than mild hearing loss (0.5, 1, 2, 3 kHz average airway hearing threshold > 25 dB on pure tone audiometry)
Exclusion Criteria
-When CNS-caused dizziness is suspected
-Symptoms after head trauma
-Past history of other otological diseases such as otitis media
-Bilateral Meniere's disease
-Taking steroids for an underlying disease
-If the affected side is the better ear (when the average airway hearing threshold of the affected side is lower than the contralateral side on pure tone audiometry)
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hearing difference between the two groups after treatment
- Secondary Outcome Measures
Name Time Method Proportion of patients who dropped out due to the need for additional treatment after treatment in both groups;Serial hearing change after treatment in both groups;Changes in vestibular function (caloric, vHIT) after treatment in both groups;Frequency of dizziness after treatment in both groups