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临床试验/NCT01390493
NCT01390493已完成1 期

Therapeutic Effects of Alpha-neurofeedback in the Treatment of Anorexia Nervosa

Medical University of Graz0 个研究点目标入组 12 人开始时间: 2010年10月1日最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
12
主要终点
brain activity in the alpha band

研究概览

简要总结

The purpose of this study is to determine whether neurofeedback training can significantly reduce the symptoms of anorexia nervosa (AN) with focus on changes in personality and psychological well-being. The primary aims of this study include:

  1. To examine whether AN patients are able to control their alpha-activity through neurofeedback.
  2. To examine the effects of neurofeedback on symptomatology and personality variables in AN patients.
  3. To examine the long-term effects of neurofeedback in the treatment of AN.

详细描述

The aim of the present study is to investigate the impact of EEG frequency band biofeedback (neurofeedback) training on EEG topography and symptomatology of patients suffering from anorexia nervosa (AN).

There is evidence that alpha-neurofeedback leads to an increase in positive therapy outcome in clinical populations by changing long-lasting EEG frequency patterns. The use of an EEG-guided relaxation paradigm has been shown to be associated with well-being and improvements in pathology of psychiatric patients.

In the present study the effects of alpha-training on EEG activity, mood, personality, well-being, blood parameters, and heart frequency will be evaluated in a sample of anorectic girls (12-18 years).

The subjects are trained with at least 10 sessions alpha-neurofeedback, in order to enhance individual alpha frequency, with spectral resting EEG, EKG, blood samples, ERP-measures and psychometric measures assessed before and after training. Neurofeedback is conducted over a period of five weeks, with each participant receiving two training sessions per-week. Neurofeedback is administered using USBAmp-EEG system.

For better surveillance of training effects there are two non-treatment control groups. A patient group receiving conventional therapy programme of the Psychosomatic Division of the Pediatric Department at the University Hospital Graz and a healthy control group.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
12 Years 至 18 Years(Child, Adult)
性别
Female
接受健康志愿者

入选标准

  • anorexia nervosa diagnosed by ICD-10

排除标准

  • epilepsy or other brain organic diseases

结局指标

主要结局

brain activity in the alpha band

时间窗: 10 sessions neurofeedback

measuring selected variables pre/posttraining and follow-up and on 10 points of measurement (10 sessions neurofeedback)

次要结局

未报告次要终点

研究者

发起方
Medical University of Graz
申办方类型
Other
责任方
Sponsor

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