Effectiveness of Rehabilitation in COPD Outpatients With Comorbidities
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Villa Pineta Hospital
- Enrollment
- 316
- Locations
- 4
- Primary Endpoint
- Nr. patients with a minimum clinically important difference (MCID) in quality of life (change in St George's Respiratory Questionnaire)
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
A retrospective analysis on a cohort of unselected COPD patients admitted to pulmonary rehabilitation (PR) performed in one rehabilitation centre has shown that the usual program is feasible and effective even in the presence of complex comorbidities, although some combined diseases might reduce the overall proportion of patients who respond to pre-defined outcomes criteria (Crisafulli E, et al. Thorax 2008;63:487-92).
The aim of this prospective study is to describe the pattern of prevalence of the most frequently associated COPD-comorbidities and the clinical impact on rehabilitation outcomes, referred to 3 teaching and 1 private hospitals admitting for pulmonary rehabilitation purposes.
Investigators
Prof. Clini Enrico
Professor
Villa Pineta Hospital
Eligibility Criteria
Inclusion Criteria
- •Presence of COPD as defined and classified according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines
- •Ability to perform a rehabilitation program.
Exclusion Criteria
- •Patients with asthma or any other pulmonary diseases (either obstructive or restrictive.
- •Patients no able to complete a rehabilitation program
Outcomes
Primary Outcomes
Nr. patients with a minimum clinically important difference (MCID) in quality of life (change in St George's Respiratory Questionnaire)
Time Frame: T0 (admission in hospital) - Tend (discharge, after 20 days)
Nr. patients with a minimum clinically important difference (MCID) in exercise tolerance (change in 6MWD)
Time Frame: T0 (admission in hospital) - Tend (discharge, after 20 days)
Nr. patients with a minimum clinically important difference (MCID) in breathless (change in MRC scale)
Time Frame: T0 (admission in hospital) - Tend (discharge, after 20 days)
Secondary Outcomes
- Percentage of patients who withdrew from rehabilitation.(Tend (discharge, after 20 days))
- Prevalence of comorbidities associated to COPD(Tend (discharge, after 20 days))