NL-OMON51582已完成4 期
The influence of having bariatric surgery on the pharmacokinetics, safety and efficacy of the novel non-nucleoside reverse transcriptase inhibitor doravirine (LABRADOR) - LABRADOR
Afdeling Apotheek0 个研究点目标入组 1 人开始时间: 待定最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 1
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- hiv-infected
- •- Viral load suppressed , below 40 copy/ml for at least 6 months, blips are
- •- planned to have bariatric surgery (gastric bypass or Sleeve gastrectomy)
- •- Able to sign informed consent
- •- Age above or equal to 18 years
- •- Using doravirine for at least 4 weeks prior to bariatric surgery with no
- •detectable viral load
排除标准
- •- History or current evidence of any condition, therapy, laboratory abnormality
- •or other circumstance that might confound the results of the study or interfere
- •with the subject*s participation
- •- Requires or is anticipated to require any of the prohibited medications known
- •to contradict/interact with doravirine
- •- Has significant hypersensitivity or other contraindication to DOR
- •- Creatinine clearance below 40 ml/min
- •- Severe liver dysfunction (Diagnosed liver cirrhosis: Child-Pugh C)
- •- Pregnancy or planning to be pregnant during first 6 months post surgery.
研究者
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