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Clinical Trials/NCT01622387
NCT01622387
Withdrawn
Not Applicable

Randomised, Controlled Trial Comparing Angiographic Patency of the Radial Artery Versus the Saphenous Vein Used as Free Aorto-coronary Grafts in Coronary Revascularisation (RSVP Trial) - 10-year Follow-up

Imperial College London1 site in 1 countryOctober 13, 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Coronary Artery Disease
Sponsor
Imperial College London
Locations
1
Primary Endpoint
Proportion of radial artery and saphenous vein grafts patent at 10 years
Status
Withdrawn
Last Updated
7 years ago

Overview

Brief Summary

During coronary bypass surgery, veins are taken from the leg and applied to the heart and aorta to 'bypass' narrowings in the coronary arteries. However using an artery in the chest, the internal mammary artery, means that the bypass lasts longer than using veins. The investigators recently showed that using an artery from the arm as a bypass vessel, the radial artery, also had less furring up than veins 5 years after surgery. Now the investigators would like to ask patients to come back for an angiogram 10 years following surgery.

Registry
clinicaltrials.gov
Start Date
October 13, 2011
End Date
July 3, 2014
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Included in the RSVP study
  • Willing to attend for coronary angiography
  • Willing to give written informed consent

Exclusion Criteria

  • Contraindication to coronary angiography
  • participation in research project within previous 60 days
  • unwilling to give written informed consent

Outcomes

Primary Outcomes

Proportion of radial artery and saphenous vein grafts patent at 10 years

Time Frame: 10 years post surgery

Comparison of the patency of radial artery and long saphenous aorto-coronary bypass grafts at 10 years, assessed by an independent observer

Secondary Outcomes

  • Patency (patent or complete occlusion, and secondary visual grading) of radial artery and internal mammary artery coronary bypass grafts(10 years post surgery)
  • Angiographic visual grading(10 years post surgery)

Study Sites (1)

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