Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Heart Failure With Preserved Ejection Fraction
- 发起方
- Chongqing Medical University
- 入组人数
- 172
- 试验地点
- 1
- 主要终点
- death
- 状态
- 已完成
- 最后更新
- 3年前
概览
简要总结
Study of the prognosis of patients with heart failure with preserved ejection fraction
详细描述
Obesity is an independent risk factor for heart failure with preserved ejection fraction (HFpEF), however, the impact of visceral fat area (VFA) in patients with HFpEF is unclear. According to established process of patients' selection, a total of 172 patients whose mean age was 72 years were included in this study, and the median follow-up duration was 395.5 days(interquartile range: 207.5 to 535.5 days). All patients were divided into two groups based on the best cut-off value of VFA, and the primary outcome of this study was all-cause death in patients with HFpEF. The aim of this study was to clarify whether VFA has prognostic value in patients with HFpEF by Kaplan-Meier analysis and cox analysis.
研究者
Dongying Zhang
clinical professor
Chongqing Medical University
入排标准
入选标准
- •Adult aged \>=18years old;
- •Diagnosed with HFpEF.Diagnostic criteria including:
- •1）left ventricular ejection fraction ≥50%； 2）with the symptoms and/or signs of heart failure； 3）BNP≥35 pg/mL and/or NTproBNP≥125 pg/mL； 4）at least one additional criterion: relevant structural heart disease(LVH and/or LAE) or diastolic dysfunction
排除标准
- •Age \<18 years old；
- •LVEF less than 45% at any time;
- •cancer diagnosis.
结局指标
主要结局
death
时间窗: The median follow-up time of 395.5 days(interquartile range: 207.5 to 535.5 days)
all-cause death