NCT04672850Unknown不适用
The Effect of Probiotic and Zinc Supplementation on the Common Cold in Healthy Adults
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Symptoms severity
研究概览
简要总结
The purpose with this study is to investigate the preventative effect of a supplement containing a combination of probiotic bacteria and fungi as well as zinc on the common cold. The hypothesis is that it will shorten the duration, alleviate the severity of symptoms or even decrease the number of infectons during the intervention period. This study is a randomzed placebo controlled human study were healthy adults will consume the supplement for three months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
Double-blinded
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults
排除标准
- •Diagnosed gastrointestinal disorders
- •Autoimmune diseases or immuno compromized
- •Antibiotic treatment in the last month
研究组 & 干预措施
Placebo
Placebo Comparator
Rice flour
干预措施: Placebo (Dietary Supplement)
Probiotic
Active Comparator
Probiotic bacteria, yeast, zinc and rice brand
干预措施: Probiotic (Dietary Supplement)
结局指标
主要结局
Symptoms severity
时间窗: Three months
Decrease in the severity of symptoms will be determined using a common cold questionnaire.
次要结局
- IgA(Three months)
- Composition of gut and oral microbiome(Three months)
- Duration of symptoms(Three months)
- Number of colds(Three months)
研究者
研究点 (1)
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