Omega-3 fatty acids on platelet and endothelial function in patients with peripheral arterial disease

Completed

• Conditions: Peripheral arterial disease; Circulatory System

• Registration Number: ISRCTN54802970
• Lead Sponsor: niversity of Aberdeen (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10-29
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

1. Able to give informed consent
2. Have an ankle brachial pressure index (ABPI) less than 0.8
3. On a statin and aspirin
4. Must be able to attend the nurse-led claudication clinic
5. Aged 35 - 90 years, either sex

Strict attention will be paid to secondary risk factor prevention as per our local guidelines. These include measures to achieve the target blood pressure (less than 140/85 mmHg), screening for diabetes, referral to smoking cessation clinic, nicotine replacement therapy and advice on exercise.

Exclusion Criteria

1. Rest pain or ulceration, liver impairment or abnormal platelet count or diabetes
2. On clopidogrel, warfarin or non-steroidal anti-inflammatory drugs

Study & Design

• Study Type: Interventional
• Study Design: Not specified