Assessment of Handgrip Strength in Adults With Inflammatory Bowel Disease

• Conditions: Nutrition; Inflammatory Bowel Disease

• Registration Number: NCT02950779
• Lead Sponsor: University of Southampton

Brief Summary

Inflammatory bowel disease (IBD) is a chronic disease, which causes inflammation of the gut. People with this disease are often poorly nourished. Problems caused by poor nutrition such as poor wound healing can be reduced if it is recognised and treated early.

When people with IBD attend outpatients clinic with their IBD specialist they are weighed and their BMI calculated to indicate if they are poorly nourished. Weight and BMI may not always provide a good assessment of how well nourished a person is because it does not describe the amount of muscle in the body in proportion to fat. A person with a low or decreasing amount of muscle but a normal or high BMI is at risk of nutritional problems. Measuring the amount of muscle someone with IBD has in routine practice poses a challenge to clinicians due to time constraints. One-way of measuring the amount of muscle a person has is to measure their muscle strength. This can be measured by recording the strength of a person's handgrip. Handgrip strength can be measured using a hand-held device called a dynamometer.

This study aims to test whether it is possible to measure the handgrip strength of people with IBD attending outpatient's clinic. It also aims to test how the measure obtained compares with other methods of assessing whether someone is malnourished and their health. People with a diagnosis of IBD who are aged 18 or older and who are scheduled to attend IBD outpatients clinic in one hospital will be asked to take part in the study. Their handgrip strength will be measured each time they attend clinic over a nine-month period in addition to other information about their health and nutritional state. This study forms part of a Masters in Research being undertaken with The University of Southampton.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-10
• Study Start: 2016-10
• Study First Submitted: 2016-10-28
• Study First Submitted QC: 2016-10-31
• Last Update Submitted: 2016-10-31
• Study First Posted: 2016-11-01
• Last Update Posted: 2016-11-01
• Primary Completion: 2017-08
• Study Completion: 2017-10

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

1. Adult participants with a confirmed diagnosis of IBD (≥18 years of age)
2. People deemed to have capacity to consent
3. People able to understand and read English
4. People attending a gastroenterology outpatient clinic appointment

Exclusion Criteria

1. People physically unable to complete the study procedures
2. Any person who is currently participating in another research trial in which the principle investigator is not satisfied to sign a 12-week exemption form.
3. People involved in an interventional study.
4. People who are currently an inpatient

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Handgrip strength measurement	12 months

Secondary Outcome Measures

Name	Time	Method
Quality of life Assessment	12 Months
IBD Disease activity	12 months
Physical Activity Assessment	12 months
Malnutrition Screening score	12 months
Micronutrient values	12 months