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临床试验/NCT01194544
NCT01194544Unknown不适用

The Relationship Between Dietary Habit and Gastroesophageal Flap Valve Abnormality

Taipei Medical University WanFang Hospital1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2010年8月最近更新:
适应症

试验速览

阶段
不适用
入组人数
600
试验地点
1
主要终点
Grading of Gastroesophageal Flap Valve by Esophagoduodenoscopy

研究概览

简要总结

Gastroesophageal reflux disease (GERD) is commonly seen in Western countries; however, it is gaining prevalence in Asia countries recently. In addition to the lower esophageal sphincter and the crural fibers of the diaphragm, the flap valve at the gastroesophageal junction is also responsible for maintaining an antireflux barrier. Hill et al developed a grading system of gastroesophageal flap valve (GEFV) and concluded that this flap valve system is simple, reproducible, and offers diagnostic aid in the evaluation of patients with suspicious reflux disease undergoing esophagogastroduodenoscopy (EGD). It is a common belief that large meals provoke considerable postprandial reflux and it results from an increase in the rate of transient lower esophageal sphincter relaxations. One study also revealed that rapid food intake produces more gastroesophageal reflux in healthy volunteers. So this study attempted to evaluate the relationship between dietary habit and GEFV abnormality. The investigators used a questionnaire regarding the dietary habit to the population undergoing EGD in a self-paid health examination.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • The healthy subjects undergo EGD in a self-paid health examination in WanFang Hospital.

排除标准

  • 未提供

结局指标

主要结局

Grading of Gastroesophageal Flap Valve by Esophagoduodenoscopy

时间窗: 1 year

Dietary habit questionnaire

时间窗: 1 year

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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