Improving the Nutrition Status of 6 to 8 Months Old Children Through Diet Diversification and Better Dietary Intakes in the Kabale and Kisoro Districts in South-Western Uganda
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Infant Malnutrition
- Sponsor
- University of Oslo
- Enrollment
- 511
- Locations
- 1
- Primary Endpoint
- Change in the prevalence of stunting (<-2 SD of the WHO, 2006 growth reference standards)
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
Undernutrition and growth restriction due to poor diet and inadequate nutrient intake continues to be a global challenge, particularly in the developing countries including Uganda. The etiology of inadequate nutrient supply to infants may relate to lack of resources or knowledge or a combination of both. Poor nutrient intake and impaired growth may affect brain and cognitive development.
This study aims to evaluate nutrient intake, growth and cognitive function among children between 6 and 36 months living in the fertile Kabale and Kisoro region in south-western Uganda. The investigators hypothesize that nutrition education to mothers can bring about improved dietary intake and nutritional status among children aged 6-36 months.
A follow-up study was conducted during the period January - July 2022.
Investigators
Per Ole Iversen, MD
Professor
University of Oslo
Eligibility Criteria
Inclusion Criteria
- •A lead caretaker with a 6-8 months infant (child/lead caretaker pair) who will have given consent to participate in the study. If there is more than one child of the age in the household, the younger one will be taken as the index/study child.
Exclusion Criteria
- •Is older than 8 months at baseline
- •Congenital malformations or physical handicap that may influence growth or interfere with taking of anthropometric measurements
- •Disability that will influence nutrient intake
- •Been diagnosed with mental or brain illness as evidenced by mother or health worker.
- •If the family that is likely to emigrate during the study period
Outcomes
Primary Outcomes
Change in the prevalence of stunting (<-2 SD of the WHO, 2006 growth reference standards)
Time Frame: 6-8, 12-16, 20-24 (main outcome time point), 36 months, 7-10 years
The investigators will measure the change in stunting between the three indicated time points.
Secondary Outcomes
- Oral health(7-10 years)
- Change in mean weight-for-age z-score(6-8, 12-16 and 20-24, 36 months, 7-10 years)
- Change in mean weight-for-height z-score(6-8, 12-16, 20-24, 36 months, 7-10 years)
- Change in mean diet diversification score (DDS)(6-8, 12-16, 20-24, 36 months)
- Change in The Kaufman Assessment Battery for Children (2nd ed.; KABC-II) and the Test of Variable of Attention (TOVA)(7-10 years)
- Change in Bayley Child Development test 3 ed.(6-8, 12-16, 20-24, 36 months)
- Change in gut microbiota(20-24, 36 months, 7-10 years)
- Change in Becks Depression Inventory II questionnaire to determine the maternal self-reported depression symptoms(7-10 years)
- Change in Mullens test(36 months)
- Change in the Center for Epidemiological Studies Depression Scale questionnaires to determine the maternal self-reported depression symptoms(7-10 years)
- Change in mean Mid Upper Arm Circumference (MUAC) z-score(6-8, 12-16, 20-24, 36 months, 7-10 years)
- Change in Ages and Stages Questionnaire Scores (AQS)(6-8, 12-16, 20-24, 36 months)
- Change in oral microbiota(36 months, 7-10 years)