NL-OMON32210
Recruiting
N/A
Phase I/II study for patients with newly diagnosed glioblastoma testing nelfinavir in combination with concomitant temozolomide and radiotherapy. - Phase I/II study with nelfinavir and radiochemotherapy for glioblastoma
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- glioblastoma
- Sponsor
- Academisch Ziekenhuis Maastricht
- Enrollment
- 58
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Histological confirmed glioblastoma multiforme at primary diagnosis
- •Tumours which do enhance on pre\-operative imaging
- •Age \>\=18\-70
- •WHO performance status 0\-2, RTOG\- RPA class III\-IV.
- •No recent (\< 3 months) severe cardiac disease (arrhythmia, congestive heart failure, infarction)
- •Willing and able to comply with the study prescriptions
- •Have given written informed consent before patient registration
- •Patient able to tolerate full course of radiotherapy
- •No previous radiotherapy to the head and neck area.
- •Prior neurosurgery within 6 weeks of treatment
Exclusion Criteria
- •the opposite of the above
Outcomes
Primary Outcomes
Not specified
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