COMPARISON OF CLINICO-RADIOLOGICAL AND FUNCTIONAL OUTCOMES BETWEEN LOCAL PLATELET RICH PLASMA(PRP) INJECTION VERSUS CONVENTIONAL TREATMENT MODALITY FOR LATERAL ANKLE SPRAIN INJURIES: RANDOMIZED CONTROL STUDY
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- 1. To compare the pain on VAS (Visual Analog Scale) score at 0, 6, and 24 weeks of PRP injection
概览
简要总结
Brief Summary: Lateral ankle sprain is a common injury, especially in young active individuals, most often involving the anterior talofibular ligament. Although conservative management provides good recovery in most cases, many patients develop chronic ankle instability. Platelet rich plasma (PRP) therapy has shown potential in enhancing soft tissue healing due to its high concentration of growth factors. This study aims to evaluate the clinical effectiveness of autologous PRP in acute lateral ankle sprain using pain and function scores, and to assess its effect on ligament quality by analyzing the signal to noise ratio of the anterior talofibular ligament on ultrasound imaging.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENT AGED 18-60 YEARS FIRST TIME LATERAL ANKLE SPRAIN DURATION OF INJURY LESS THAN 48 HOURS OF INJURY GRADE 2 MILD TO MODERATE INSTABILITY.
排除标准
- 未提供
结局指标
主要结局
1. To compare the pain on VAS (Visual Analog Scale) score at 0, 6, and 24 weeks of PRP injection
时间窗: 0,6,24 WEEKS
2. To compare the ankle functional outcomes based on AOFAS score at 0,6, and 24 weeks of PRP injection
时间窗: 0,6,24 WEEKS
次要结局
- To compare the Foot & ankle disability index (FADI) at 0, , 6, & 24 weeks of PRP injection
- To compare the ankle functional outcomes based on ankle ultrasound scan evaluation at 0,6 and 24 weeks(2.To compare the foot and ankle disability index at 0,2,6,12 and 24 weeks)
研究者
RAJESH KUMAR RAJNISH
AIIMS JODHPUR