Examination of effects of aggressive antihypertensive therapy on renal and vascular endothelial function - ATTACK ( Antihypertensive Therapy for vascular endothelial function and kidney)

Study group for vascular protection0 sites200 target enrollmentJanuary 1, 2024

Overview

No summary available.

Registry

who.int

Start Date

January 1, 2024

End Date

August 1, 2010

Last Updated

2 years ago

Study Type

Interventional

Sex

Male

Sponsor

Study group for vascular protection

•1\) Patients with overt nephropathy (microalbuminuria more than 300 mg/g Cr) 2\) Patients with uncontrolled hypertension (systolic blood pressure more than 180mmHg or diastolic blood pressure more than 110mmHg at the time of informed consent) 3\) Patients with malignant hypertension 4\) Patients with secondary hypertension 5\) Patients with liver dysfunction (ALT or AST over three times the normal value) 6\) Patients with a previous history of gout attack 7\) Patients who have critical cardiovascular complications that required hospitalization within 6 months prior to informed consent 8\) Pregnant or breast feeding female patients, including one trying to conceive pregnancy during the planned study period 9\) Patients with cardiac insufficiency (above NYHA grade III) 10\) Patients with uncontrolled arrhythmia 11\) Patients under treatment with diuretics 12\) Patients with a history of hypersensitivity to ingredients of the study drugs 13\) Patients who are considered not eligible for the study by the attending doctor due to medical reasons