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临床试验/CTRI/2024/06/068681
CTRI/2024/06/068681尚未招募3 期

Randomized open labelled comaprative clinical study to evaluate the efficacy of Nasya with Anutaila prepared with rain water and ro water in Hairfall with special reference to Khalitya.

Dr Bhanushree S1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年7月30日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Hairfall rate,60 sec haircount, Hair pull test,Trichoscopy findings(if required).

研究概览

简要总结

Good-looking and attractive hair is a person’s natural jewellery, In today’s beauty concerned world, overlook of hair becomes a prime and important factor. Around 70% of men may experience hair loss in their lifetime, compared to only 40% of women.

In Ayurvedic science, increased falling of hair is termed asKhalitya i.e.Khalati Skalayanti Kesa Asmatha .Ayurveda mentions, to obtain Arogya,Aishwarya, Yasha inthe Loka, one should abide the lifestyle mentioned in the context of Dinacharya and Rutucharya. In the context of Dinacharya, Acharya has mentioned procedures like Moordhni Taila,Nasya(Pratimarsha variety),Snana etc*.*which can be taken intoconsideration for  importance in the prevention of Khalitya.

Acharya Charaka has mentioned Kesha as a Mala of Asthi Dhatu along with Vata Dosha predominance, and according to Acharya Sharngadhara it is a Upadhatu of Majja Dhatu.

In general, one can lose up to 50 to 100 hairs per day,if the cycle is disrupted or a follicle is damaged, hair may begin to fall out more quickly. Due to changes in the lifestyle in contributes with the role of pollutants, climatic variation, stress, anxiety, work pressure, sedentary life style, improper care of the health, genetics etc., is intensifying the hair fall problems of the society in the early stage of

individual’s life i.e., 20s and 30s.

In contemporary science, the treatment protocol mentioned for hair loss is based on underlying conditions and nutritional supplements, with hair serum, platelet rich plasma technique, hair transplant etc. which has limitations due to its side effects and may not be feasible for everyone.

Hence*,* it is necessary to conduct a study which would be helpful to manage hair fall with no side effects when compared to the available contemporary treatments.

Nasya karma is one among the panchakarma where Aushadha is administered through nasal route, nourishes the Shiras, Skandha, Greeva and Urdhwajatru**pradesha. Acharya Sushrutamentions“Khalitya Cha Api Asambhavah” this unmasks the importance of Nasya Karma in the Khalitya.

According to Acharya Charaka, Dehoshma along with Vatadi Dosha causes Khalitya. Nasya with Sneha Dravya due to its Guna and Karma will pacify the vitiated Vata Dosha and provides the nourishment to the Shiras. In Charaka Samhita, Acharya has mentioned the importance of Anutaila as “Na Cha Kesha Pramuchyante Vardhante Cha Visheshatah” i.e., it prevents the falling of hairs as well as promotes the healthy growth of the hairs.

Also*, Acharya Vagbhata* mentioned, Anatariksha Jala as Amrutopamam with Jeevana and Tarpana Guna. But at present, in the Pharmacy available formulation, Anatariksha Jala is replaced with RO water as we have room to build up various sources to procure water, which may have various significance on preparation.

Hence, an attempt is made to study and compare the efficacy of Nasya with Anutaila prepared with Rain water and RO water in the management ofHairfall*(Khalitya).*

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
21.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Subjects in between the age group of 21 – 45years.
  • Subjects who complain of shedding of scalp hairs.
  • Subjects of either gender who are Nasya Yogyas according to Ayurveda classics irrespective of their occupation and socio-economic status.
  • Subjects who are willing to give a written consent for the treatment.

排除标准

  • Subject who are undergoing hair treatment, chemotherapy, radiation therapy.
  • Pregnant and lactating women.
  • Subjects unfit for Nasya Karma.
  • Subjects having any active scalp disease, Androgenetic alopecia, Alopecia areata and hair transplant.
  • Subjects with any known history systemic diseases and nutritional deficiencies which interfere treatment protocol and intervention.
  • Subjects of chronic alcoholic and psychiatric illness.

结局指标

主要结局

Hairfall rate,60 sec haircount, Hair pull test,Trichoscopy findings(if required).

时间窗: Oth day,7th day,14th day

次要结局

未报告次要终点

研究者

发起方
Dr Bhanushree S
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Bhanushree S

Sri Sri College Of Ayurvedic Science and Research

研究点 (1)

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