MRD in High-risk EBC
- Conditions
- Breast Cancer
- Registration Number
- NCT06566729
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- Female
- Target Recruitment
- 125
Inclusion Criteria:<br><br> - Informed consent signed<br><br> - Age =18 years old<br><br> - Undergoing breast surgery, the surgical specimen was diagnosed as invasive breast<br> cancer by the central laboratory and met any of the following conditions:<br><br> 1. Hormone receptor-positive/HER2-negative breast cancer, the number of lymph node<br> metastases = 4;<br><br> 2. HER2-positive breast cancer, lymph node metastasis=4;<br><br> 3. Triple negative breast cancer, the number of lymph node metastases = 1;<br><br> - ECOG 0-1<br><br> - Willing to cooperate in clinical research-related treatment and follow-up, with good<br> patient compliance<br><br>Exclusion Criteria:<br><br> - Confirmed distant metastases site<br><br> - History of other malignancy<br><br> - Psychopaths or other reasons unable to comply with treatment<br><br> - Concomitant uncontrolled lung disease, severe liver and kidney disease, severe<br> infection, active peptic ulcer requiring treatment, coagulation disorders,<br> connective tissue disease, or bone marrow suppression, and cannot tolerate<br> chemotherapy and other related treatments<br><br> - HIV carrier or HBC/HCV infected<br><br> - Current or recent (within 30 days prior to enrollment) use of participation in<br> another investigational program or use of another investigational drug
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relapse-free survival
- Secondary Outcome Measures
Name Time Method Overall survival;Lead time