Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation

Not Applicable

Completed

• Conditions: Atrial Fibrillation

• Registration Number: NCT00272636
• Lead Sponsor: University of Michigan

Brief Summary

The purpose of this study is to determine the long-term efficacy of radiofrequency catheter ablation in patients with chronic atrial fibrillation.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-11
• Study Completion: 2005-02
• Status Verified: 2006-01
• Study First Submitted: 2006-01-03
• Study First Submitted QC: 2006-01-03
• Study First Posted: 2006-01-06
• Last Update Submitted: 2015-06-02
• Last Update Posted: 2015-06-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• Chronic atrial fibrillation

Exclusion Criteria

• Left atrial diameter >55 mm
• Left ventricular ejection fraction <0.30
• Contraindication to amiodarone therapy or anticoagulation with warfarin
• Presence of a mechanical prosthetic valve
• History of a cerebrovascular accident
• Presence of left atrial thrombus on TEE
• Prior attempt at catheter or surgical ablation for atrial fibrillation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Freedom from atrial fibrillation and atrial flutter in the absence of antiarrhythmic drug therapy at 1 year.

Secondary Outcome Measures

Name	Time	Method
changes in left atrial diameter
changes in left ventricular ejection fraction
changes in symptom severity
incidence of complications

Trial Locations

Locations (2)

University of Michigan Health System; 🇺🇸 Ann Arbor, Michigan, United States

San Raffaele Hospital; 🇮🇹 Milan, Italy