Effect of Exercise Training After Percutaneous Coronary Intervention
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Helse Stavanger HF
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- flow mediated dilation, serum concentrations of biomarkers, restenosis-rate/ late luminal loss, heart rate variability in SDNN
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The Efector study is an open, randomized and controlled trial assessing the effect of regular exercise training on endothelial function, inflammatory markers, progression of disease, heart rate variability and mental health in patients who have been successfully treated with percutaneous coronary intervention and stent implantation for angina pectoris.
Detailed Description
Pas er randomized to a 6 months training group or none training. At baseline and at 6 months patients are examined with blood tests to measure serum concentrations of inflammatory markers, a test for endothelial function, heart rate variability and a coronary angiogram. Further patients are asked to answer questionnaires concerning mental health (SF36, HADS).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Successful PCI with stent implantation,
- •Able to participate in the training program,
- •No planned further revascularisation
Exclusion Criteria
- •Inflammatory diseases other than CAD,
- •Heart failure,
- •Severe kidney failure,
- •Inability to participate in the training program
Outcomes
Primary Outcomes
flow mediated dilation, serum concentrations of biomarkers, restenosis-rate/ late luminal loss, heart rate variability in SDNN
Time Frame: 6 months
Secondary Outcomes
- Oxygen uptake capacity (mg/kg/min), Sf36 scores(6 months)