Effect of Propofol Cardioplegia Solution on Myocardial Injury Bio marker
Phase 3
- Conditions
- atherosclerosis.Atherosclerotic heart disease
- Registration Number
- IRCT20180922041084N2
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Patient who are candidate for elective Coronary Artery Bypass surgery
Exclusion Criteria
Redo surgery
Primary troponin level is above 3 µg / L
sever Renal failure
sever Liver failure
congestive Heart Failure grade IV
Ejection fraction lower than 30%
Allergy to eggs, soy, peanuts
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of troponin I. Timepoint: 1st sample just after induction ,2nd sample just after chest closure , 3rd sample 6 hours after arrival to ICU and last sample 24 hours after arrival to the ICU. Method of measurement: Lab test.;Serum level of CPKMB. Timepoint: 1st sample just after induction ,2nd sample just after chest closure , 3rd sample 6 hours after arrival to ICU and last sample 24 hours after arrival to the ICU. Method of measurement: Lab test.
- Secondary Outcome Measures
Name Time Method Arhytmia. Timepoint: During operation and after that. Method of measurement: Monitoring.