Intervention trial for colorectal cancer prevention by endoscopic polypectomy in patients with familial adenomatous polyposis
Phase 1
- Conditions
- familial adenomatous polyposis
- Registration Number
- JPRN-UMIN000009365
- Lead Sponsor
- AMED
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 222
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who are considered by their attending physicians to be ineligible to participate in the study because they have a serious disease in other organs, or because they cannot discontinue antiplatelet drugs, or for other reasons. Patients who are receiving anticancer drugs. Patients with dense FAP in at least one-third of the large intestine. Patients in whom strict follow-up is difficult.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Whether or not a patient needs surgery on the large intestine during the intervention period. It includes not only the development of a polyp that cannot be removed endoscopically or that of large intestinal cancer, but also cases where a patient wishes to undergo resection of the large intestine because of discomfort of endoscopic examination, and cases where emergency surgery is performed because of perforation occurred during endoscopic treatment.
- Secondary Outcome Measures
Name Time Method Presence or absence of the development of adverse events (perforation, hemorrhage, death from large intestinal cancer, and death from other causes), colorectal cancer, intramucosal carcinoma, or a tumor that is difficult to treat endoscopically.